It was shown in the fourth experiment that injections of muscimol into a more medial p. In the third experiment, it was again demonstrated that 25.0 ng of muscimol injected directly into the substantia nigra pars reticulata blocked the jaw movements induced by tacrine in addition, it was shown that injections of this dose 2.0 mm dorsal to the substantia nigra pars reticulata failed to affect tacrine-induced tremulous jaw movements. However, injections of muscimol (12.5-50 ng) into the substantia nigra pars reticulata blocked the jaw movements induced by tacrine. Injections of muscimol into the entopeduncular nucleus (25-100 ng) failed to have any significant effects on tacrine-induced vacuous jaw movements. Because there are GABAergic projections from neostriatum to entopeduncular nucleus (medial globus pallidus) and substantia nigra pars reticulata, the GABA agonist muscimol was injected directly into these structures to study the effects of GABA stimulation on tacrine-induced jaw movements. Thus, the present study investigated potential striatal output pathways that could be involved in the generation of these movements. Previous work has shown that the tremulous jaw movements induced by cholinomimetics and dopamine depletion are dependent upon striatal mechanisms. 1919, William MacLeod Raine, A Man Four-Square, ch.
3: The trying nature of his position drove the blood from his cheek, and made his lips tremulous.
1850, Nathaniel Hawthorne, The Scarlet Letter, ch. injections of the anticholinesterase tacrine (5.0 mg/kg). tremulous (comparative more tremulous, superlative most tremulous) Trembling, quivering, or shaking. In these experiments, tremulous jaw movements were induced by i.p. Four experiments were conducted to investigate the role of pallidal and nigral GABA in the generation of tremulous jaw movements in rats. as, a tremulous limb a tremulous motion of the hand or the lips the tremulous leaf of the poplar.